ADVANCE study provides new insights into the management of SHPT in CKD patients Results from the Progress study presented in a late breaking clinical trial program at the ERA-EDTA 2010 Congress provide new insights in to the management of secondary hyperparathyroidism in chronic kidney disease patients Click to read more . A trend was observed towards slower progression of vascular calcification at all sites evaluated among sufferers randomised to the cinacalcet arm, although primary endpoint didn’t reach statistical significance. The primary endpoint for the scholarly study was %age change in the Agatston CAC score from baseline to week 52.
The experts used medical details extracted from the UK Clinical Practice Research Datalink from the Hospital Episodes Figures database. The analysis included men newly diagnosed with nonmetastatic prostate cancers between January 1997 and December 2008 who were followed up until December 2009. Cases were individuals with incident AKI during follow-up who were randomly matched with up to 20 controls on age group, twelve months of prostate cancer medical diagnosis, and duration of follow-up. Analysis was executed to estimate the chances ratios of AKI associated with the use of ADT.